Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 7/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108942 | 1.00 | MEP1B (0.59) | MEP1BPARP1FOLH1IDH1TSHR | |
| SCHEMBL4944580 | 0.89 | PARP1 (0.50) | MEP1BPARP1 | |
| SCHEMBL5645749 | 0.85 | PARP1 (0.53) | MEP1BPARP1FOLH1IDH1TSHR | |
| SCHEMBL29572523 | 0.83 | ATM (0.52) | MEP1BFOLH1TSHRTDP1L3MBTL1 | |
| SCHEMBL185962 | 0.83 | ATM (0.52) | MEP1BFOLH1TSHRTDP1L3MBTL1 | |
| SCHEMBL2062793 | 0.83 | CES2 (0.48) | MEP1BFOLH1TSHRCES2CES1 | |
| SCHEMBL17672270 | 0.83 | PLA2G2A (0.59) | MEP1BPARP1FOLH1IDH1TSHR | |
| SCHEMBL2822360 | 0.82 | PARP1 (0.50) | MEP1BPARP1FOLH1IDH1KDM1A | |
| SCHEMBL8173564 | 0.82 | MEP1B (0.66) | MEP1BPARP1IDH1 | |
| SCHEMBL509423 | 0.82 | LOXL2 (0.66) | MEP1BPARP1FOLH1IDH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939288-B | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-118613257-A | Tetrahydropyrazolopyrimidines and related analogs for the inhibition of YAP/TAZ-TEAD | 鲁汶大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |