Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 3/20 | 0.36 |
| ▸ | CDK8 | P49336 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613173 | 0.95 | CDC7 (0.41) | CDC7USP7ADORA2ATRPA1MTOR | |
| SCHEMBL30896370 | 0.79 | SCN9A (0.38) | TRPA1CCNCCDK8AR | |
| SCHEMBL15345075 | 0.79 | TRPA1 (0.48) | CDC7USP7TRPA1DYRK1ACLK1 | |
| SCHEMBL30896399 | 0.77 | PIK3CD (0.46) | IRAK4GRM2 | |
| SCHEMBL680695 | 0.77 | AXL (0.41) | CDC7USP7TRPA1IRAK4GRM2 | |
| SCHEMBL30896383 | 0.77 | ADORA2A (0.47) | ADORA2AMTORDYRK1APIK3CBNFATC1 | |
| SCHEMBL31613166 | 0.76 | TRPA1 (0.37) | TRPA1CCNCCDK8AR | |
| SCHEMBL31613172 | 0.76 | KDM4E (0.44) | MTORDYRK1APIK3CBNFATC1CLK1 | |
| SCHEMBL30896379 | 0.75 | PIK3CD (0.41) | IRAK4GRM2 | |
| SCHEMBL30896396 | 0.75 | ATAD2 (0.49) | CDC7MTORDYRK1APIK3CBIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |