Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896385 | 0.82 | ATAD2 (0.54) | ATAD2PDE3BPDE3AS100BPIK3CB | |
| SCHEMBL30896317 | 0.79 | MAPK14 (0.47) | PDE3BPDE3AGRM2MAP4K4CDC7 | |
| SCHEMBL30896325 | 0.79 | MAPT (0.44) | PDE3BPDE3A | |
| SCHEMBL30896404 | 0.78 | KDM4E (0.44) | CCNCCDK8PIK3CBMAP4K4PDE10A | |
| SCHEMBL31613172 | 0.78 | KDM4E (0.44) | CCNCCDK8PIK3CBMAP4K4PDE10A | |
| SCHEMBL30896383 | 0.76 | ADORA2A (0.47) | CCNCCDK8PIK3CBMAP4K4PDE10A | |
| SCHEMBL30896357 | 0.75 | CDC7 (0.41) | CCNCCDK8GRM2PIK3CBMAP4K4 | |
| SCHEMBL31613173 | 0.75 | CDC7 (0.41) | CCNCCDK8GRM2PIK3CBMAP4K4 | |
| SCHEMBL30896384 | 0.71 | MAPK1 (0.46) | — | |
| SCHEMBL7086532 | 0.70 | CCNC (0.43) | CCNCCDK8PIK3CBMAP4K4CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |