Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613168 | 0.94 | KDM4E (0.46) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL6199167 | 0.89 | KDM4E (0.53) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL25219471 | 0.83 | SMN1; SMN2 (0.41) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL28392846 | 0.79 | KDM4E (0.58) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL11874680 | 0.77 | ALDH1A1 (0.41) | LMNAKDM4EALDH1A1MAPTHTT | |
| SCHEMBL588563 | 0.76 | RAB9A (0.62) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL20358007 | 0.75 | RAB9A (0.60) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL4664889 | 0.74 | LMNA (0.40) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30896380 | 0.74 | ALDH1A1 (0.40) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30896387 | 0.73 | MAPT (0.59) | LMNAKDM4EALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |