Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613172 | 0.95 | KDM4E (0.44) | KDM4EALDH1A1LMNAMAPTMAP4K4 | |
| SCHEMBL30896312 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1LMNAMAPTCYP11B2 | |
| SCHEMBL30896396 | 0.78 | ATAD2 (0.49) | MAP4K4CCNCCDK8DYRK1APDE10A | |
| SCHEMBL30896380 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAMAPTCYP11B2 | |
| SCHEMBL31613173 | 0.76 | CDC7 (0.41) | MAP4K4CCNCCDK8DYRK1AMTOR | |
| SCHEMBL6200788 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1LMNAMAPTDYRK1A | |
| SCHEMBL30896357 | 0.73 | CDC7 (0.41) | MAP4K4CCNCCDK8DYRK1AMTOR | |
| SCHEMBL30896395 | 0.73 | PRKCI (0.40) | MAP4K4CYP11B2CCNCCDK8PIK3CB | |
| SCHEMBL30896383 | 0.71 | ADORA2A (0.47) | MAP4K4CCNCCDK8DYRK1APDE10A | |
| SCHEMBL7086532 | 0.68 | CCNC (0.43) | MAP4K4CCNCCDK8DYRK1AMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |