Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613188 | 0.94 | HSD17B10 (0.40) | GAAHSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL22449397 | 0.77 | ALDH1A1 (0.56) | GAAHSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL17338776 | 0.75 | FGFR1 (0.55) | GAAHSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL31613171 | 0.73 | TDP1 (0.38) | GAAHSD17B10TDP1KDM5B | |
| SCHEMBL31613186 | 0.72 | L3MBTL1 (0.41) | GAAMAPTALDH1A1HPGDPKM | |
| SCHEMBL22449395 | 0.71 | ALDH1A1 (0.53) | GAAHSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL25335407 | 0.71 | PRPS1 (0.44) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL31062044 | 0.71 | PRPS1 (0.44) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL30896413 | 0.71 | TDP1 (0.38) | GAAHSD17B10ALDH1A1PKMTDP1 | |
| SCHEMBL7033971 | 0.70 | FGFR1 (0.52) | GAAHSD17B10MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |