Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449395 | 0.94 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL17338776 | 0.90 | FGFR1 (0.55) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL1594855 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL7033971 | 0.84 | FGFR1 (0.52) | ALDH1A1MAPTHPGDGAAHSD17B10 | |
| Imidazole SCHEMBL28191367 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL1864820 | 0.80 | HCAR1 (0.52) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL20986012 | 0.77 | PKM (0.58) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL12075901 | 0.77 | FGFR1 (0.48) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL12075903 | 0.77 | FGFR1 (0.48) | ALDH1A1MAPTHPGDPKMGAA | |
| SCHEMBL30896410 | 0.77 | GAA (0.40) | ALDH1A1MAPTHPGDPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787420-B2 | Benzimidazole compound and preparation method thereof | SHANDONG ENGINEERING AND TECHNOLOGY INSTITUTE OF LUNAN COAL CHEMICAL ENGINEERING (CN) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787420-B2 | Benzimidazole compound and preparation method thereof | NISCH, AZI2, HNMT | ALDH1A1 1585/4885MAPT 3334/4885HPGD 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.