Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142590 | 1.00 | DGAT1 (0.36) | DGAT1KMT2AGAABRD4CREBBP | |
| SCHEMBL22717793 | 0.83 | BRD4 (0.36) | DGAT1KMT2AGAABRD4CREBBP | |
| SCHEMBL29907301 | 0.82 | KMT2A (0.38) | DGAT1KMT2ABRD4CREBBPKDM4E | |
| SCHEMBL27139837 | 0.82 | KMT2A (0.38) | DGAT1KMT2ABRD4CREBBPKDM4E | |
| SCHEMBL22717531 | 0.82 | KDM4E (0.40) | DGAT1KMT2AGAABRD4CREBBP | |
| SCHEMBL18248884 | 0.79 | AGER (0.38) | DGAT1KMT2ABRD4CREBBPALDH1A1 | |
| SCHEMBL29495244 | 0.78 | NPC1 (0.40) | DGAT1KMT2ABRD4CREBBPMEN1 | |
| SCHEMBL28722469 | 0.78 | NPC1 (0.40) | DGAT1KMT2ABRD4CREBBPMEN1 | |
| SCHEMBL15122763 | 0.77 | HTT (0.42) | DGAT1BRD4CREBBPPOLBTDP1 | |
| SCHEMBL30897277 | 0.77 | BRD4 (0.37) | DGAT1KMT2AGAABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602047-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | The Universite de Montreal (CA) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |