Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722469 | 1.00 | NPC1 (0.40) | NPC1DPP4BRD4CREBBPPARP1 | |
| SCHEMBL18248884 | 0.89 | AGER (0.38) | NPC1BRD4CREBBPDGAT1KMT2A | |
| SCHEMBL22717531 | 0.87 | KDM4E (0.40) | BRD4CREBBPDGAT1MEN1LMNA | |
| SCHEMBL15122763 | 0.82 | HTT (0.42) | NPC1BRD4CREBBPSMN1; SMN2DGAT1 | |
| SCHEMBL22717793 | 0.79 | BRD4 (0.36) | NPC1DPP4BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL5591449 | 0.79 | LMNA (0.39) | NPC1DPP4BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL30897282 | 0.78 | DGAT1 (0.36) | NPC1BRD4CREBBPSMN1; SMN2DGAT1 | |
| SCHEMBL27142590 | 0.78 | DGAT1 (0.36) | NPC1BRD4CREBBPSMN1; SMN2DGAT1 | |
| SCHEMBL30938018 | 0.77 | P2RX3 (0.46) | NPC1DPP4BRD4CREBBPP2RX3 | |
| SCHEMBL15122465 | 0.77 | FGFR1 (0.48) | NPC1BRD4CREBBPSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |