Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | STK4 | Q13043 | 1/20 | 0.35 |
| ▸ | STK3 | Q13188 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898614 | 0.89 | BRD4 (0.40) | BRD4TDP2PDE4BPDK2ROCK2 | |
| SCHEMBL30898661 | 0.89 | BRD4 (0.40) | BRD4TDP2PDE4BPDK2ROCK2 | |
| SCHEMBL30898657 | 0.79 | TDP2 (0.38) | BRD4TDP2PDE4BPDK2ROCK2 | |
| SCHEMBL22479318 | 0.74 | PIK3CA (0.41) | AKT1 | |
| SCHEMBL30898718 | 0.72 | MAP3K14 (0.44) | BRD4TDP2PDK2MAP3K14STK4 | |
| SCHEMBL30898683 | 0.71 | TDP2 (0.43) | TDP2PDK2MAP3K14STK4STK3 | |
| SCHEMBL30898666 | 0.70 | TDP2 (0.45) | BRD4TDP2PDK2ROCK2STK4 | |
| SCHEMBL30898642 | 0.68 | EZH2 (0.45) | PDE4BMEN1KMT2AAKT1 | |
| SCHEMBL30898644 | 0.67 | TDP2 (0.43) | TDP2PDK2MAP3K14STK4STK3 | |
| SCHEMBL22122380 | 0.66 | PIK3CA (0.38) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631541-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |