Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | OTUD7B | Q6GQQ9 | 5/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898640 | 0.86 | TDP2 (0.46) | TDP2MAP3K14CRBNPDK2ERN1 | |
| SCHEMBL30898666 | 0.84 | TDP2 (0.45) | TDP2CRBNPDK2ERN1EZH2 | |
| SCHEMBL30898618 | 0.81 | MAPK14 (0.57) | TDP2OTUD7BMAP3K14CRBNMAPK14 | |
| SCHEMBL30898684 | 0.76 | TDP2 (0.49) | TDP2OTUD7BMAP3K14BACE1PDK2 | |
| SCHEMBL17444524 | 0.76 | KDM1A (0.43) | PDK2BRD4MAPK14 | |
| SCHEMBL31390939 | 0.73 | MAPK14 (0.43) | PDK2MAPK14 | |
| SCHEMBL22058140 | 0.72 | KDM1A (0.40) | PDK2MAPK14 | |
| SCHEMBL11091537 | 0.71 | TNKS (0.37) | EZH2 | |
| Bromide SCHEMBL20954964 | 0.71 | KDM1A (0.39) | PDK2MAPK14 | |
| SCHEMBL30468541 | 0.71 | TSHR (0.40) | PDK2EZH2BRD4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |