Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898611 | 0.86 | EZH2 (0.39) | EZH2MAPK14CDC7CDK9 | |
| SCHEMBL30898671 | 0.80 | SLC18A3 (0.37) | EZH2OPRK1OPRD1OPRM1DRD2 | |
| SCHEMBL30898651 | 0.73 | EZH2 (0.48) | EZH2OPRK1OPRD1OPRM1OPRL1 | |
| SCHEMBL30898713 | 0.73 | EZH2 (0.48) | EZH2OPRK1OPRD1OPRM1OPRL1 | |
| SCHEMBL30898695 | 0.70 | TDP2 (0.43) | DRD2DRD3CCNCCDK8MAPK14 | |
| SCHEMBL30898642 | 0.65 | EZH2 (0.45) | EZH2CCNCCDK8HASPINCDC7 | |
| SCHEMBL30898645 | 0.64 | EZH2 (0.41) | EZH2OPRK1OPRD1OPRM1OPRL1 | |
| SCHEMBL3216850 | 0.64 | GAA (0.58) | DRD3POLB | |
| SCHEMBL3226312 | 0.62 | ALDH1A1 (0.48) | POLB | |
| SCHEMBL22479372 | 0.61 | OPRL1 (0.52) | EZH2OPRK1OPRD1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |