Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.45 |
| ▸ | OTUD7B | Q6GQQ9 | 6/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PRF1 | P14222 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898703 | 0.76 | TDP2 (0.46) | TDP2BACE1MAP3K14OTUD7BPDK2 | |
| SCHEMBL30898618 | 0.75 | MAPK14 (0.57) | TDP2MAP3K14OTUD7B | |
| SCHEMBL12747661 | 0.71 | BACE1 (0.45) | BACE1BRD4 | |
| SCHEMBL22770435 | 0.71 | GPR119 (0.46) | OPRM1OPRD1OPRK1 | |
| SCHEMBL24389029 | 0.70 | USP30 (0.56) | BACE1 | |
| SCHEMBL3728008 | 0.70 | AOC3 (0.57) | — | |
| SCHEMBL27457057 | 0.70 | SIGMAR1 (0.73) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL17355225 | 0.69 | PGR (0.47) | BACE1HTR2CHTR2BSIGMAR1BRD4 | |
| SCHEMBL12748158 | 0.69 | PGR (0.47) | BACE1BRD4 | |
| SCHEMBL7889463 | 0.68 | PGR (0.46) | BACE1HTR2CHTR2BSIGMAR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |