Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.45 |
| ▸ | CA1 | P00915 | 13/20 | 0.45 |
| ▸ | CA9 | Q16790 | 12/20 | 0.45 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.45 |
| ▸ | CA5A | P35218 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061829 | 1.00 | CA2 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL10914937 | 0.82 | CA2 (0.50) | CA2CA1CA9CA12CA6 | |
| SCHEMBL2187405 | 0.81 | MYC (0.41) | CDK2 | |
| SCHEMBL9633042 | 0.73 | CA2 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL30673446 | 0.73 | CA2 (0.46) | CA2CA1CA9CA12CA6 | |
| SCHEMBL31388625 | 0.73 | CA2 (0.43) | CA2CA1CA9CA12CA6 | |
| SCHEMBL30262415 | 0.72 | CA1 (0.41) | CA2CA1CA9CA12 | |
| SCHEMBL17093012 | 0.71 | CA2 (0.52) | CA2CA1CA9CA12CA6 | |
| SCHEMBL18796166 | 0.71 | ALDH1A1 (0.43) | CA2CA1CA12CA5ACA4 | |
| SCHEMBL27516440 | 0.71 | NR1H2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956992-A | MENIN-MLL interaction inhibitors | 赛达克斯制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |