Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936937 | 0.82 | RAB9A (0.35) | EGFRCLK4 | |
| SCHEMBL29550394 | 0.77 | TRPV1 (0.33) | EGFRGSK3ACDK9CDK5TAOK1 | |
| SCHEMBL30657083 | 0.77 | GRM4 (0.38) | EGFR | |
| SCHEMBL24464882 | 0.77 | NQO2 (0.41) | EGFREGLN1GSK3ACDK9CDK5 | |
| SCHEMBL19587070 | 0.77 | CCR1 (0.36) | EGFR | |
| SCHEMBL24615675 | 0.77 | GRM4 (0.38) | EGFR | |
| SCHEMBL29439776 | 0.77 | EPRS1 (0.35) | — | |
| SCHEMBL19878479 | 0.73 | NQO2 (0.45) | EGFR | |
| SCHEMBL30493870 | 0.73 | HPGDS (0.36) | — | |
| SCHEMBL31645421 | 0.73 | PARP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |