Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903073 | 0.85 | POLB (0.33) | POLB | |
| SCHEMBL31275019 | 0.84 | LMNA (0.34) | LMNAPOLBKDM4ETAS1R3TAS1R1 | |
| SCHEMBL30903029 | 0.81 | TAS1R3 (0.39) | LMNAKDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31274678 | 0.72 | POLB (0.33) | POLBKDM4EKMT2A | |
| SCHEMBL25414277 | 0.71 | LMNA (0.36) | LMNAKDM4EMEN1KMT2ATAS1R3 | |
| SCHEMBL31275328 | 0.70 | — | — | |
| SCHEMBL30903081 | 0.69 | TAS1R3 (0.37) | LMNAPOLBKDM4ETAS1R3TAS1R1 | |
| SCHEMBL20186726 | 0.69 | ALDH1A1 (0.45) | LMNAPOLBKDM4EMEN1KMT2A | |
| SCHEMBL30903033 | 0.69 | HSP90AB1 (0.45) | LMNAKDM4E | |
| SCHEMBL31458976 | 0.67 | LMNA (0.33) | LMNAKDM4ETAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105563-A1 | SUBSTITUTED BICYCLIC PYRIDONE DERIVATIVES | PFIZER INC. (US) | 2024-05-23 | — | — | WO | disclosed |