Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25411583 | 0.87 | CCR2 (0.36) | RAB9ACCR2KDM4EOPRM1OPRL1 | |
| SCHEMBL31275019 | 0.86 | LMNA (0.34) | POLBRAB9ACBLBKDM4E | |
| SCHEMBL31275328 | 0.84 | — | — | |
| SCHEMBL30872144 | 0.82 | ALDH1A1 (0.38) | POLBRAB9ACBLBCCR2KMT2A | |
| SCHEMBL30903073 | 0.81 | POLB (0.33) | POLBCYP17A1 | |
| SCHEMBL31459001 | 0.75 | MAPT (0.32) | POLBCCR2KDM4E | |
| SCHEMBL31275111 | 0.75 | S1PR2 (0.39) | KMT2A | |
| SCHEMBL31459244 | 0.73 | S1PR2 (0.34) | RAB9ACCR2 | |
| SCHEMBL30872137 | 0.73 | TAS1R3 (0.39) | CCR2OPRM1OPRL1 | |
| SCHEMBL30903067 | 0.72 | LMNA (0.33) | POLBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255762-A1 | CBL-B INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2024-12-19 | — | — | WO | disclosed |