Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.51 |
| ▸ | GRN | P28799 | 3/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30168116 | 0.98 | RIPK1 (0.50) | RIPK1GRNSORT1PYGLCYP2C9 | |
| SCHEMBL30168114 | 0.87 | RIPK1 (0.47) | RIPK1GRNSORT1TSHR | |
| SCHEMBL30219105 | 0.86 | RIPK1 (0.51) | RIPK1GRNSORT1 | |
| SCHEMBL30219049 | 0.86 | RIPK1 (0.51) | RIPK1GRNSORT1 | |
| Hydrochloric Acid SCHEMBL30219092 | 0.85 | RIPK1 (0.50) | RIPK1GRNSORT1 | |
| SCHEMBL30219101 | 0.84 | CTSL (0.50) | RIPK1GRNSORT1 | |
| SCHEMBL30219112 | 0.84 | CTSL (0.50) | RIPK1GRNSORT1 | |
| SCHEMBL30219068 | 0.82 | RIPK1 (0.46) | RIPK1GRNSORT1PYGLCYP2C9 | |
| SCHEMBL30219104 | 0.82 | RIPK1 (0.46) | RIPK1GRNSORT1PYGLCYP2C9 | |
| SCHEMBL27165633 | 0.82 | RIPK1 (0.46) | RIPK1GRNSORT1PYGLCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | disclosed |