SCHEMBL30903625

SCHEMBL30903625

Brc1ccc2nc(-c3ccccc3)sc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.71
KDM4E B2RXH2 7/20 0.66
MAPT P10636 6/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
GLA P06280 4/20 0.66
GAA P10253 4/20 0.66
ALDH1A1 P00352 4/20 0.66
PKM P14618 2/20 0.66
HPGD P15428 2/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
NFKB1 P19838 3/20 0.62
NFKB2 Q00653 3/20 0.62
RELA Q04206 3/20 0.62
LMNA P02545 3/20 0.62
RAB9A P51151 7/20 0.51
NPC1 O15118 6/20 0.51
TP53 P04637 2/20 0.51
POLB P06746 2/20 0.51
HSD17B10 Q99714 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15414023 1.00 APP (0.71) APPKDM4EMAPTSMN1; SMN2GLA
Dimethylamine SCHEMBL2524428 0.94 APP (0.72) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL31120302 0.89 APP (0.81) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL595453 0.86 KDM4E (0.57) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL2461395 0.83 APP (1.00) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL4157441 0.83 APP (0.72) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL14075967 0.83 APP (0.72) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL4806067 0.83 APP (0.72) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL17801714 0.83 NPC1 (0.66) APPKDM4EMAPTSMN1; SMN2GLA
SCHEMBL12408902 0.82 KDM4E (0.70) APPKDM4EMAPTSMN1; SMN2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250169358-A1 Organic Compound, And Organic Light Emitting Diode And Organic Light Emitting Device Including The Same LG DISPLAY CO., LTD. (KR) 2025-05-22 US disclosed
CN-119841790-A Method for preparing 2-substituted benzothiazole derivatives by driving light 中国科学院大连化学物理研究所 2025-04-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250169358-A1 Organic Compound, And Organic Light Emitting Diode And Organic Light Emitting Device Including The Same AOX1, ODC1, OR51E2 APP 1042/4885KDM4E 3212/4885MAPT 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.