SCHEMBL15414023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30903625	1.00	APP (0.71)	APPKDM4EMAPTSMN1; SMN2GLA
	Dimethylamine SCHEMBL2524428	0.94	APP (0.72)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL31120302	0.89	APP (0.81)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL595453	0.86	KDM4E (0.57)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL2461395	0.83	APP (1.00)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL4157441	0.83	APP (0.72)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL14075967	0.83	APP (0.72)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL4806067	0.83	APP (0.72)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL17801714	0.83	NPC1 (0.66)	APPKDM4EMAPTSMN1; SMN2GLA
	SCHEMBL12408902	0.82	KDM4E (0.70)	APPKDM4EMAPTSMN1; SMN2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.