Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650876 | 0.74 | KDM4E (0.45) | ABCB1SLC6A4HRH3DRD2LMNA | |
| SCHEMBL27843034 | 0.73 | EPHX1 (0.44) | SLC6A4DRD2SLC6A2SLC6A3KDM4E | |
| SCHEMBL23914107 | 0.71 | HRH3 (0.40) | ABCB1ADRA1ASLC6A4HRH3DRD2 | |
| SCHEMBL23913811 | 0.69 | ALDH1A1 (0.40) | ABCB1SLC6A4HRH3DRD2LMNA | |
| Hydrochloric Acid SCHEMBL7256239 | 0.68 | DRD2 (0.68) | SLC6A4HRH3DRD2HTR2AHTR7 | |
| SCHEMBL5329929 | 0.66 | KDM1A (0.47) | SLC6A4DRD2LMNASLC6A2SLC6A3 | |
| SCHEMBL5699414 | 0.66 | KDM1A (0.50) | SLC6A4DRD2LMNASLC6A2SLC6A3 | |
| SCHEMBL694466 | 0.66 | KDM1A (0.50) | SLC6A4DRD2LMNASLC6A2SLC6A3 | |
| SCHEMBL807336 | 0.65 | ACHE (0.66) | DRD2CRHBPCRHR2LMNAKDM4E | |
| SCHEMBL19419117 | 0.65 | EPHX1 (0.45) | SLC6A4LMNASLC6A2SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227645-B2 | Cyclisation process of forming a multiple ring compound | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-07-24 | — | — | US | disclosed |
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228058-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | DHPS, GGPS1, COASY | ABCB1 4098/4885ADRA1A 3581/4885SLC6A4 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.