Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401343 | 0.88 | PKMYT1 (0.40) | TDP2MAPTNPSR1ADORA2ABRD4 | |
| SCHEMBL30905510 | 0.88 | PKMYT1 (0.40) | TDP2MAPTNPSR1ADORA2ABRD4 | |
| SCHEMBL27397408 | 0.88 | IKBKB (0.41) | MAPTADORA2ABRD4PKMYT1 | |
| SCHEMBL30905539 | 0.88 | IKBKB (0.41) | MAPTADORA2ABRD4PKMYT1 | |
| SCHEMBL30905520 | 0.87 | CACNB4 (0.40) | MAPTNPSR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL27401510 | 0.87 | CACNB4 (0.40) | MAPTNPSR1CACNB4CACNA1ACACNA1G | |
| SCHEMBL30905489 | 0.82 | GABRG2 (0.42) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL27401986 | 0.82 | GABRG2 (0.42) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30905515 | 0.76 | BRD4 (0.45) | TDP2MAPTBRD4ACHE | |
| SCHEMBL27401200 | 0.76 | BRD4 (0.45) | TDP2MAPTBRD4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |