Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935674 | 0.79 | ALDH1A1 (0.38) | CA12CA14CA2DGAT1GAA | |
| SCHEMBL10010655 | 0.79 | TSHR (0.48) | CA12CA14TSHRHSD17B10MGAM | |
| SCHEMBL28346522 | 0.77 | PAM (0.36) | DGAT1TSHRGAAHDAC6APLNR | |
| SCHEMBL31364246 | 0.77 | HDAC6 (0.35) | DGAT1GAAHDAC6APLNRHDAC1 | |
| SCHEMBL28299938 | 0.76 | ALDH1A1 (0.35) | CA12CA14CA2DGAT1TET2 | |
| SCHEMBL303763 | 0.76 | DGAT1 (0.41) | CA12CA14CA2DGAT1GAA | |
| SCHEMBL3134646 | 0.76 | HDAC6 (0.34) | DGAT1HDAC6APLNRHDAC1HDAC2 | |
| SCHEMBL16746703 | 0.75 | NAAA (0.44) | TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16265197 | 0.74 | HDAC6 (0.33) | CA2DGAT1GAAHDAC6APLNR | |
| SCHEMBL16593852 | 0.74 | HDAC6 (0.33) | DGAT1GAAHDAC6APLNRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077087-A2 | M24B AMINOPEPTIDASE INHIBITORS FOR CARDS INFLAMMASOME ACTIVATION | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-04-11 | — | — | WO | disclosed |