Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31527564 | 0.78 | LMNA (0.43) | NOS1LMNAMAPTQPCTPIK3CA | |
| SCHEMBL30907657 | 0.74 | SMN1; SMN2 (0.35) | LMNAMAPTPIK3CAALDH1A1MEN1 | |
| SCHEMBL30589324 | 0.74 | QPCT (0.40) | LMNAMAPTQPCTPIK3CAALDH1A1 | |
| SCHEMBL30316855 | 0.74 | QPCT (0.45) | NOS1LMNAMAPTQPCTALDH1A1 | |
| SCHEMBL21061503 | 0.74 | QPCT (0.40) | LMNAMAPTQPCTPIK3CAALDH1A1 | |
| SCHEMBL15661441 | 0.74 | LMNA (0.44) | NOS1LMNAMAPTQPCTPIK3CA | |
| SCHEMBL24457836 | 0.74 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27089082 | 0.73 | APLNR (0.43) | NOS1LMNAMAPTQPCTALDH1A1 | |
| SCHEMBL30000304 | 0.73 | APLNR (0.43) | NOS1LMNAMAPTQPCTALDH1A1 | |
| SCHEMBL26005022 | 0.72 | LMNA (0.45) | NOS1LMNAMAPTQPCTPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |