Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102740 | 0.88 | TRPA1 (0.59) | MAPTDPP4TRPA1KMOCES1 | |
| SCHEMBL3101794 | 0.85 | DPP4 (0.72) | DPP4TRPA1PPARGPPARAKMO | |
| 4-Chloro-Benzoic Acid SCHEMBL10391602 | 0.83 | ALOX15 (0.59) | MAPTL3MBTL1TRPA1PPARGPPARA | |
| SCHEMBL9554501 | 0.83 | KMO (0.72) | MAPTL3MBTL1PPARGPPARAKMO | |
| SCHEMBL7319589 | 0.83 | KMO (0.72) | MAPTL3MBTL1PPARGPPARAKMO | |
| SCHEMBL3105307 | 0.81 | HPGD (0.54) | MAPTPPARGPPARAPOLBGSK3B | |
| SCHEMBL24157467 | 0.80 | MAPT (0.55) | MAPTL3MBTL1PPARGPPARAPDPK1 | |
| SCHEMBL3102314 | 0.80 | NPC1 (0.61) | MAPTL3MBTL1DPP4PPARGPPARA | |
| SCHEMBL24157470 | 0.80 | MAPT (0.55) | MAPTL3MBTL1PPARGPPARAPDPK1 | |
| SCHEMBL6464257 | 0.78 | PPARG (0.53) | L3MBTL1TRPA1PPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249243-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | PULKKINEN JUHA | 2010-09-30 | — | — | US | disclosed |
| US-20100249243-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | PULKKINEN JUHA | 2010-09-30 | — | — | US | disclosed |
| US-20100249243-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | PULKKINEN JUHA | 2010-09-30 | — | — | US | disclosed |
| WO-2009066008-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | PULKKINEN JUHA (FI) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249243-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | HSD17B11, HSD17B7, CYP19A1 | MAPT 4143/4885L3MBTL1 4833/4885DPP4 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.