Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | GLP1R | P43220 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29980480 | 0.79 | GLP1R (0.49) | ALDH1A1KDM4EGLP1RHPGDKMT2A | |
| SCHEMBL20338486 | 0.79 | GLP1R (0.49) | ALDH1A1KDM4EGLP1RHPGDKMT2A | |
| SCHEMBL4960456 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAANPC1HPGD | |
| SCHEMBL30908510 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4EGLP1RGAANPC1 | |
| SCHEMBL30285938 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAANPC1HPGD | |
| SCHEMBL949288 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAANPC1HPGD | |
| Acridine SCHEMBL8000372 | 0.71 | ALDH1A1 (0.65) | ALDH1A1KDM4EGAANPC1HPGD | |
| SCHEMBL358560 | 0.71 | TDP1 (0.59) | ALDH1A1KDM4EGAANPC1HPGD | |
| SCHEMBL30099865 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAANPC1HPGD | |
| Acridine SCHEMBL2140243 | 0.70 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |