Sugi Predict

Sugi Predict / Compounds / Acridine

Acridine

Acridine

SCHEMBL2140243

NS(N)(=O)=O.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.71
▸ HPGD P15428 3/20 0.71
▸ MAPT P10636 3/20 0.71
▸ GLA P06280 2/20 0.71
▸ ACHE P22303 1/20 0.71
▸ HTR3A P46098 1/20 0.57
▸ KDM4E B2RXH2 6/20 0.50
▸ GAA P10253 4/20 0.50
▸ NPC1 O15118 3/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ POLB P06746 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ PTBP1 P26599 1/20 0.50
▸ RCE1 Q9Y256 1/20 0.50
▸ NQO2 P16083 1/20 0.48
▸ CA12 O43570 2/20 0.47
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL10831095 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1051621 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL11600717 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL25171236 0.86 ALDH1A1 (0.58) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8339 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29352289 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL3045498 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL4972293 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1772714 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL23458139 0.82 LMNA (0.61) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112684163-B Acridine compound marking raw material working solution and preparation method thereof 安邦（厦门）生物科技有限公司 2022-08-09 — — CN claimed
CN-113624964-A Detection method and detection kit for invasive fungi 上海市第十人民医院 2021-11-09 — — CN claimed
CN-112684163-A Acridine compound marking raw material working solution and preparation method thereof 安邦（厦门）生物科技有限公司 2021-04-20 — — CN claimed
CN-109283171-B Screening method of chemiluminescent reagent stabilizer 苏州长光华医生物医学工程有限公司 2020-04-28 — — CN claimed
CN-109517036-B Lung carcinoma cell specific binding polypeptide and preparation method thereof 拜西欧斯（北京）生物技术有限公司 2019-10-08 — — CN claimed
CN-109517036-A Lung carcinoma cell specific binding polypeptide and preparation method thereof 拜西欧斯（北京）生物技术有限公司 2019-03-26 — — CN claimed
CN-108445214-A A kind of kit and preparation method quantitatively detecting d-dimer 浙江艾明德生物科技有限公司 2018-08-24 — — CN claimed
CN-108445222-A A kind of kit and preparation method quantitatively detecting cardic fatty acid binding protein 浙江艾明德生物科技有限公司 2018-08-24 — — CN claimed
CN-108445215-A A kind of kit and preparation method quantitatively detecting myeloperoxidase 浙江艾明德生物科技有限公司 2018-08-24 — — CN claimed
CN-108089007-A A kind of kit and preparation method for quantitatively detecting c reactive protein 浙江艾明德生物科技有限公司 2018-05-29 — — CN claimed
CN-105652018-A C-peptide quantitative determination kit 广州科方生物技术有限公司 2016-06-08 — — CN claimed
CN-115308423-B Biomarkers, kits and methods for risk prediction, assessment or diagnosis of preeclampsia 天津云检医疗器械有限公司 2023-02-10 — — CN disclosed
CN-115656153-A Antinuclear antibody spectrum detection kit based on acridinium ester chemiluminescence 广东优尼德生物科技有限公司 2023-01-31 — — CN disclosed
CN-115575384-A Folic acid detection kit and detection method 北京乐普诊断科技股份有限公司 2023-01-06 — — CN disclosed
CN-112964874-B SARS-CoV-2 detecting reagent kit based on indirect method 深圳市亚辉龙生物科技股份有限公司 2022-11-01 — — CN disclosed
US-20110054175-A1 SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2011-03-03 — — US disclosed
CN-101038255-B Capillary electrophoresis chemiluminescence detector of acridiniumester, acridine sulfonamide and marker thereof, and method thereof UNIV FUZHOU 2010-05-19 — — CN disclosed
WO-2009100014-A1 SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-08-13 — — WO disclosed
CN-101281196-A HIV-1 p24 antigen acridine ester chemiluminescence immune analyse detecting method UNIV BEIJING TECHNOLOGY (CN) 2008-10-08 — — CN disclosed
CN-101038255-A Capillary electrophoresis chemiluminescence detector of acridiniumester, acridine sulfonamide and marker thereof, and method thereof UNIV FUZHOU (CN) 2007-09-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054175-A1 SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS PFAS, ODC1, AOC1 ALDH1A1 969/4885HPGD 3285/4885MAPT 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.