Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22511690 | 0.82 | NOS1 (0.65) | NOS1NOS2NOS3 | |
| SCHEMBL13349521 | 0.80 | RECQL (0.47) | NOS1NOS3CSNK2A1CA12CA2 | |
| SCHEMBL12891556 | 0.80 | CYP1A2 (0.45) | NOS1NOS3CYP2A6 | |
| SCHEMBL1599287 | 0.80 | NOS1 (0.38) | NOS1NOS2NOS3 | |
| SCHEMBL27795596 | 0.79 | HRH3 (0.50) | NOS1NOS2LOXLOXL3LOXL2 | |
| SCHEMBL30908293 | 0.77 | NOS1 (0.36) | NOS1NOS2NOS3 | |
| SCHEMBL27956204 | 0.74 | CA2 (0.50) | CA2 | |
| SCHEMBL22933038 | 0.74 | NOS1 (0.49) | NOS1NOS2NOS3 | |
| SCHEMBL24954764 | 0.72 | LMNA (0.60) | — | |
| SCHEMBL22511767 | 0.72 | NQO1 (0.44) | NOS1NOS2LOXL2NOS3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |