Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13349521 | 0.85 | RECQL (0.47) | NOS1NOS3KDM4ECYP3A4CYP2C19 | |
| SCHEMBL12891556 | 0.77 | CYP1A2 (0.45) | NOS1NOS3KDM4ECYP3A4CYP2C19 | |
| SCHEMBL30908359 | 0.77 | NOS1 (0.48) | NOS1NOS3NOS2 | |
| SCHEMBL1599287 | 0.77 | NOS1 (0.38) | NOS1NOS3KDM4ECYP3A4CYP2C19 | |
| SCHEMBL27956204 | 0.75 | CA2 (0.50) | KDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL21458200 | 0.72 | RECQL (0.46) | KDM4ECYP3A4CYP2C19HIF1ARECQL | |
| SCHEMBL30718745 | 0.72 | RECQL (0.46) | KDM4ECYP3A4CYP2C19HIF1ARECQL | |
| SCHEMBL22933038 | 0.71 | NOS1 (0.49) | NOS1NOS3NOS2 | |
| SCHEMBL18572376 | 0.70 | CCR9 (0.34) | NOS1NOS3KDM4ECYP3A4CYP2C19 | |
| SCHEMBL622672 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |