Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17657691 | 0.82 | POLB (0.58) | KDM4EPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30908143 | 0.79 | ALDH1A1 (0.40) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL8936155 | 0.78 | POLB (0.72) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL3420261 | 0.78 | POLB (0.52) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL5517317 | 0.78 | MAPT (0.51) | KDM4EPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9828211 | 0.77 | LMNA (0.47) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL1600117 | 0.75 | KDM4E (0.49) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL5434270 | 0.75 | KDM4E (0.50) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL5437258 | 0.75 | KDM4E (0.49) | KDM4ECYP3A4CYP2C19HIF1APOLB | |
| SCHEMBL7424524 | 0.75 | CYP2C19 (0.49) | KDM4ECYP3A4CYP2C19HIF1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |