Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223679 | 0.87 | TRPM5 (0.45) | LMNAL3MBTL1DHFRALDH1A1TSHR | |
| SCHEMBL17657691 | 0.80 | POLB (0.58) | L3MBTL1DHFRALDH1A1TSHRCYP1A2 | |
| SCHEMBL9828612 | 0.77 | F2 (0.56) | LMNAL3MBTL1DHFRALDH1A1TSHR | |
| SCHEMBL8936095 | 0.77 | POLB (0.64) | LMNAL3MBTL1DHFRALDH1A1CYP1A2 | |
| SCHEMBL30908463 | 0.77 | KDM4E (0.46) | LMNAL3MBTL1DHFRALDH1A1CYP1A2 | |
| SCHEMBL4586080 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AAOX1TRIM24 | |
| SCHEMBL423891 | 0.74 | L3MBTL1 (0.71) | LMNAL3MBTL1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL30081464 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP1A2KMT2AAOX1 | |
| SCHEMBL4586476 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP1A2KMT2AAOX1 | |
| SCHEMBL7003951 | 0.71 | CCR1 (0.44) | LMNAL3MBTL1DHFRALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1991-12-04 | — | — | EP | disclosed |
| EP-0096214-B1 | ANTIBACTERIAL PYRIMIDINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-02-27 | — | — | EP | disclosed |
| US-4587341-A | BACTERICIDES | BURROUGHS WELLCOME CO. (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |