Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820710 | 0.82 | GBA1 (0.37) | ALDH1A1KDM4ECYP2C19RAB9ANPC1 | |
| SCHEMBL30908504 | 0.81 | L3MBTL1 (0.46) | ALDH1A1KDM4ECYP2C19MAPTCYP2C9 | |
| SCHEMBL15877470 | 0.79 | CYP2C19 (0.38) | ALDH1A1KDM4ECYP2C19RAB9ANPC1 | |
| SCHEMBL1817853 | 0.75 | GBA1 (0.39) | ALDH1A1KDM4ERAB9ANPC1TSHR | |
| SCHEMBL30908459 | 0.75 | GBA1 (0.39) | ALDH1A1KDM4ERAB9ANPC1TSHR | |
| SCHEMBL1002566 | 0.73 | CYP2C19 (0.48) | ALDH1A1KDM4ECYP2C19RAB9ANPC1 | |
| SCHEMBL15118626 | 0.73 | LMNA (0.41) | ALDH1A1KDM4ECYP2C19RAB9ANPC1 | |
| SCHEMBL14466870 | 0.72 | LMNA (0.40) | ALDH1A1KDM4ECYP2C19RAB9ANPC1 | |
| SCHEMBL1063890 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4ERAB9ANPC1TSHR | |
| SCHEMBL29630882 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4ERAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |