Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725934 | 1.00 | OPRM1 (0.36) | OPRM1OPRK1HCRTR1MAPTTDP1 | |
| SCHEMBL8706037 | 0.89 | ALDH1A1 (0.42) | HCRTR1MAPTTDP1TP53ALDH1A1 | |
| SCHEMBL8721276 | 0.88 | AVPR1A (0.44) | MAPTTP53ALDH1A1KDM4EAVPR2 | |
| SCHEMBL8720711 | 0.87 | TP53 (0.44) | MAPTTDP1TP53KMT2AMEN1 | |
| SCHEMBL8721052 | 0.85 | HRH3 (0.41) | MAPTTP53HRH3 | |
| SCHEMBL30909156 | 0.85 | HRH3 (0.41) | MAPTTP53HRH3 | |
| SCHEMBL8725926 | 0.84 | TDP1 (0.41) | MAPTTDP1TP53ALDH1A1POLB | |
| SCHEMBL8721911 | 0.84 | KMT2A (0.43) | MAPTTDP1TP53ALDH1A1KDM4E | |
| SCHEMBL8724051 | 0.83 | AKR1C3 (0.38) | OPRM1OPRK1MAPTHRH3SMN1; SMN2 | |
| SCHEMBL8720635 | 0.83 | HRH3 (0.34) | MAPTTDP1TP53HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |