Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 3/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721052 | 1.00 | HRH3 (0.41) | HRH3ACKR3KCNK3KCNK9F2R | |
| SCHEMBL8706037 | 0.86 | ALDH1A1 (0.42) | ACKR3TP53MAPT | |
| SCHEMBL8721276 | 0.85 | AVPR1A (0.44) | TP53MAPT | |
| SCHEMBL8721780 | 0.85 | HCRTR1 (0.39) | HRH3PNLIPCNR1CNR2TP53 | |
| SCHEMBL30909135 | 0.85 | HCRTR1 (0.39) | HRH3PNLIPCNR1CNR2TP53 | |
| SCHEMBL30909146 | 0.85 | OPRM1 (0.36) | HRH3TP53MAPT | |
| SCHEMBL8725934 | 0.85 | OPRM1 (0.36) | HRH3TP53MAPT | |
| SCHEMBL8720711 | 0.84 | TP53 (0.44) | KCNK3KCNK9TP53MAPT | |
| SCHEMBL8724021 | 0.83 | HTR1F (0.40) | HRH3TP53MAPTMCHR1 | |
| SCHEMBL8724051 | 0.82 | AKR1C3 (0.38) | HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |