Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706037 | 0.85 | ALDH1A1 (0.42) | TDP1CYP3A4CYP2D6CYP2C19TP53 | |
| SCHEMBL8720711 | 0.84 | TP53 (0.44) | TDP1TP53MAPT | |
| SCHEMBL8721276 | 0.84 | AVPR1A (0.44) | TP53MAPTL3MBTL1 | |
| SCHEMBL8725934 | 0.83 | OPRM1 (0.36) | HRH3TDP1TP53MAPT | |
| SCHEMBL30909146 | 0.83 | OPRM1 (0.36) | HRH3TDP1TP53MAPT | |
| SCHEMBL8724021 | 0.83 | HTR1F (0.40) | HRH3TP53MAPT | |
| SCHEMBL8721911 | 0.83 | KMT2A (0.43) | HRH3TDP1TP53MAPT | |
| SCHEMBL8720679 | 0.83 | MAPK14 (0.38) | HRH3TDP1TP53MAPTL3MBTL3 | |
| SCHEMBL8724051 | 0.82 | AKR1C3 (0.38) | HRH3CYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL8720781 | 0.81 | MAPT (0.45) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |