Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775059 | 0.96 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL30909064 | 0.96 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3640167 | 0.81 | DRD2 (0.59) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL2424591 | 0.80 | DRD2 (0.58) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL12605572 | 0.78 | DRD2 (0.59) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL7570882 | 0.77 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL6742428 | 0.77 | HTR7 (0.50) | OPRM1OPRD1OPRK1OPRL1HTR7 | |
| SCHEMBL7569682 | 0.77 | HRH3 (0.40) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL17222489 | 0.77 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL15856596 | 0.77 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |