Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | VPS4B | O75351 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110880 | 1.00 | HTR1F (0.41) | HTR1FMAPTTHRBALDH1A1LMNA | |
| SCHEMBL30908864 | 0.90 | HTR1A (0.42) | HTR1FMAPTTHRBALDH1A1LMNA | |
| SCHEMBL8100859 | 0.90 | HTR1A (0.42) | HTR1FMAPTTHRBALDH1A1LMNA | |
| SCHEMBL8110886 | 0.82 | MAPT (0.34) | MAPTMAP1LC3BMAP1LC3ABRD4PDGFRB | |
| SCHEMBL8110843 | 0.77 | MEN1 (0.63) | HTR1FMAPTALDH1A1LMNAVPS4B | |
| SCHEMBL8100872 | 0.75 | HTR1A (0.35) | MAPTBRD4PDGFRBKDRPARP1 | |
| SCHEMBL8101435 | 0.74 | HTR1F (0.47) | HTR1FMAPTTHRBALDH1A1LMNA | |
| SCHEMBL8110281 | 0.74 | KIF11 (0.45) | HTR1FMAPTALDH1A1LMNAVPS4B | |
| Sulfuric Acid SCHEMBL8101053 | 0.73 | VPS4B (0.49) | HTR1FMAPTTHRBALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8110488 | 0.71 | VPS4B (0.46) | HTR1FMAPTTHRBALDH1A1VPS4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |