Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387125 | 1.00 | RAB9A (0.42) | RAB9AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8386577 | 0.84 | HTR1D (0.43) | RAB9AALDH1A1CYP3A4SMN1; SMN2DRD2 | |
| SCHEMBL8384436 | 0.83 | DRD2 (0.42) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL30908978 | 0.83 | DRD2 (0.42) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL30908902 | 0.83 | HTR2A (0.44) | KMT2ATP53MAPTDRD2HTR2A | |
| SCHEMBL8385565 | 0.83 | HTR2A (0.44) | KMT2ATP53MAPTDRD2HTR2A | |
| SCHEMBL8381707 | 0.81 | MEN1 (0.47) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL30908992 | 0.81 | MEN1 (0.47) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL8548534 | 0.81 | DRD2 (0.48) | RAB9AALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30908827 | 0.79 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |