Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911663 | 1.00 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL1554586 | 1.00 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL5237 | 0.85 | GNE (0.68) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL2532948 | 0.84 | GNE (0.66) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL1579475 | 0.83 | GNE (0.55) | RAB9ASMN1; SMN2GNEALDH1A1TP53 | |
| SCHEMBL947448 | 0.81 | HTR2C (0.54) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL3239132 | 0.81 | HTR2C (0.54) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL2594231 | 0.81 | GNE (0.50) | SMN1; SMN2GNEALDH1A1TP53MAPK1 | |
| SCHEMBL7159 | 0.81 | IRAK4 (0.50) | RAB9ANPC1SMN1; SMN2GNEALDH1A1 | |
| SCHEMBL30149935 | 0.81 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2GNEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | disclosed |