Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911663 | 1.00 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL30911660 | 1.00 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL5237 | 0.85 | GNE (0.68) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL2532948 | 0.84 | GNE (0.66) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL1579475 | 0.83 | GNE (0.55) | RAB9ASMN1; SMN2GNEALDH1A1TP53 | |
| SCHEMBL947448 | 0.81 | HTR2C (0.54) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL3239132 | 0.81 | HTR2C (0.54) | RAB9ANPC1SMN1; SMN2GNEHTR2C | |
| SCHEMBL2594231 | 0.81 | GNE (0.50) | SMN1; SMN2GNEALDH1A1TP53MAPK1 | |
| SCHEMBL7159 | 0.81 | IRAK4 (0.50) | RAB9ANPC1SMN1; SMN2GNEALDH1A1 | |
| SCHEMBL30149935 | 0.81 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2GNEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066518-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| EP-2488030-B1 | 1-(PYRID-3-YL)-PYRAZOLES AND 1-(PYRIMID-5-YL)-PYRAZOLES AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-08-07 | — | — | US | disclosed |
| EP-2488030-A1 | 1- (PYRID-3-YL) -PYRAZOLE AND 1- (PYRIMID-5-YL) -PYRAZOLE AS PESTICIDE | Bayer CropScience AG (DE) | 2012-08-22 | — | — | EP | disclosed |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| WO-2011045224-A1 | 1- (PYRID-3-YL) -PYRAZOLE AND 1- (PYRIMID-5-YL) -PYRAZOLE AS PESTICIDE | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |
| US-20080113983-A1 | Nicotinic Acetylcholine Receptor Ligands | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| US-20080113983-A1 | Nicotinic Acetylcholine Receptor Ligands | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| US-20080113983-A1 | Nicotinic Acetylcholine Receptor Ligands | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| CN-101124232-A | Nicotinic acetylcholine receptor ligands | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | CN | disclosed |
| EP-1831231-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006065209-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221362-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | RAB9A 1143/4885NPC1 3961/4885SMN1; SMN2 1914/4885 |
| US-20110166143-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, BCHE | RAB9A 1143/4885NPC1 3961/4885SMN1; SMN2 1914/4885 |
| US-20080113983-A1 | Nicotinic Acetylcholine Receptor Ligands | CHRNA1, CHRNA2, CHRNB1 | RAB9A 1451/4885NPC1 1159/4885SMN1; SMN2 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.