Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 3/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914197 | 0.81 | KDM4E (0.41) | USP2MAPK1KDM4EHIF1ANPSR1 | |
| SCHEMBL30914195 | 0.79 | MEN1 (0.49) | MEN1KMT2AKDM4EHIF1ANPSR1 | |
| SCHEMBL30914204 | 0.77 | NPC1 (0.40) | USP2MAPK1KDM4EHIF1ANPSR1 | |
| SCHEMBL31203032 | 0.76 | KDM4E (0.37) | MEN1KMT2AKDM4EHIF1ANPSR1 | |
| SCHEMBL29117046 | 0.69 | MEN1 (0.47) | MEN1KMT2ANSD3L3MBTL1NPC1 | |
| SCHEMBL1024585 | 0.64 | SMN1; SMN2 (0.73) | MEN1KMT2ALTA4HMAPTL3MBTL1 | |
| SCHEMBL28636829 | 0.64 | NSD2 (0.37) | MAPK1KDM4ENPSR1NSD2NSD3 | |
| SCHEMBL17678350 | 0.64 | MEN1 (0.68) | MEN1KMT2AUSP2MAPK1KDM4E | |
| SCHEMBL31202900 | 0.63 | MEN1 (0.61) | MEN1KMT2AUSP2MAPK1KDM4E | |
| SCHEMBL30914189 | 0.63 | MEN1 (0.61) | MEN1KMT2AMAPK1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182453-A1 | NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2024-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182453-A1 | NOVEL SUBSTITUTED PYRAZINE-CARBOXAMIDE DERIVATIVES | GRIA4, GRM4, GRM1 | MEN1 4564/4885KMT2A 1367/4885USP2 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.