SCHEMBL3091602

SCHEMBL3091602

CC(=O)C(Cc1ccc(C(=O)c2ccccc2)cc1)C(C)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.55
ALDH1A1 P00352 8/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
HTT P42858 3/20 0.50
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
PPARA Q07869 1/20 0.49
ELANE P08246 1/20 0.49
SRD5A2 P31213 2/20 0.48
ATM Q13315 2/20 0.46
HPGD P15428 4/20 0.46
RAB9A P51151 5/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
CYP19A1 P11511 1/20 0.45
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13148575 0.92 MDM2 (0.64) MDM2ALDH1A1SMN1; SMN2L3MBTL1HTT
SCHEMBL3079812 0.88 MDM2 (0.50) MDM2ALDH1A1SMN1; SMN2L3MBTL1HTT
SCHEMBL15391739 0.87 MDM2 (0.60) MDM2ALDH1A1SMN1; SMN2L3MBTL1HTT
SCHEMBL15391136 0.86 MDM2 (0.55) MDM2ALDH1A1SMN1; SMN2L3MBTL1HTT
SCHEMBL1896075 0.85 MDM2 (0.61) MDM2RAB9ANPC1LMNA
SCHEMBL16728148 0.84 SLC7A5 (0.55) MDM2ALDH1A1SMN1; SMN2L3MBTL1HTT
SCHEMBL15454767 0.83 MDM2 (0.59) MDM2RAB9ANPC1LMNA
SCHEMBL27762682 0.83 MDM2 (0.59) MDM2RAB9ANPC1LMNA
SCHEMBL9317096 0.82 LDHA (0.52) MDM2LMNA
SCHEMBL2334247 0.82 ALDH1A1 (0.50) MDM2ALDH1A1SMN1; SMN2L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203496-B1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2018-04-11 EP disclosed
EP-2203496-B1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2018-04-11 EP disclosed
US-8318830-B2 Photolatent catalysts based on organometallic compounds BASF SE (DE) 2012-11-27 US disclosed
US-8318830-B2 Photolatent catalysts based on organometallic compounds BASF SE (DE) 2012-11-27 US disclosed
US-20100234485-A1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2010-09-16 US disclosed
US-20100234485-A1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2010-09-16 US disclosed
EP-2203496-A1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2010-07-07 EP disclosed
WO-2009050115-A1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (CH) 2009-04-23 WO disclosed
WO-2009050115-A1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (CH) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234485-A1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS PUF60, TST, MPST MDM2 3500/4885ALDH1A1 1432/4885SMN1; SMN2 4860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.