Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314235 | 1.00 | KDM4E (0.54) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL21549828 | 0.85 | ELANE (0.48) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL28511558 | 0.85 | LMNA (0.50) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL29378503 | 0.82 | KDM4E (0.73) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL752535 | 0.82 | KDM4E (0.73) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL11312632 | 0.80 | TSHR (0.42) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| Phthalic Acid SCHEMBL8629198 | 0.80 | ALDH1A1 (0.54) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL29010714 | 0.79 | KDM4E (0.63) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL31543794 | 0.79 | KDM4E (0.53) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL5268362 | 0.79 | THRB (0.54) | KDM4EHSD17B10HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240423878-A2 | SELF-ADHESIVE FISSURE SEALANT | KULZER GMBH (DE) | 2024-12-26 | — | — | US | disclosed |
| US-20240216229-A1 | SELF-ADHESIVE FISSURE SEALANT | KULZER GMBH (DE) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240423878-A2 | SELF-ADHESIVE FISSURE SEALANT | ESD, GFER, FUS | KDM4E 2920/4885HSD17B10 1806/4885HPGD 819/4885 |
| US-20240216229-A1 | SELF-ADHESIVE FISSURE SEALANT | ESD, GFER, FUS | KDM4E 2920/4885HSD17B10 1806/4885HPGD 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.