SCHEMBL24407683

SCHEMBL24407683

O=C(O)c1ccc(Oc2c(F)c(F)c(F)c(F)c2F)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
TSHR P16473 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
XDH P47989 4/20 0.46
MAPT P10636 3/20 0.44
CYP3A4 P08684 2/20 0.44
GAA P10253 1/20 0.44
ESR2 Q92731 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PTPN1 P18031 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HPGD P15428 2/20 0.42
HTT P42858 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24407664 0.94 ALDH1A1 (0.49) ALDH1A1CA12CA1CA2TSHR
SCHEMBL30918587 0.84 POLB (0.54) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL8072637 0.84 POLB (0.54) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL14213143 0.84 ALDH1A1 (0.65) ALDH1A1CA12CA1CA2TSHR
SCHEMBL24407665 0.81 XDH (0.64) ALDH1A1CA12CA1CA2TSHR
SCHEMBL6567615 0.80 POLB (0.50) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL24407681 0.79 HPGD (0.40) XDHESR2HSD17B10HPGDHTT
SCHEMBL31118332 0.79 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EHSD17B10HPGD
SCHEMBL24407693 0.78 THRB (0.50) ALDH1A1CA12CA1CA2TSHR
SCHEMBL24407747 0.77 ALDH1A1 (0.45) ALDH1A1CA12CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146935-A1 CARBOXYLATE, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed