SCHEMBL30920217

SCHEMBL30920217

O=C(NCc1cc2cc(OC(F)(F)F)c(OCc3cscn3)cc2[nH]1)N1CCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 5/20 0.36
▸ CYP2C9 P11712 3/20 0.36
▸ CYP2J2 P51589 3/20 0.36
▸ GRM5 P41594 1/20 0.34
▸ MAPK1 P28482 2/20 0.33
▸ ENPP2 Q13822 2/20 0.32
▸ ATXN2 Q99700 2/20 0.32
▸ KIT P10721 1/20 0.32
▸ MET P08581 1/20 0.32
▸ KDM1A O60341 1/20 0.30
▸ NAMPT P43490 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247665 0.98 EPHX2 (0.36) EPHX2CYP2C9CYP2J2GRM5MAPK1
SCHEMBL27247554 0.89 ALK (0.34) EPHX2GRM5MAPK1MET
SCHEMBL30946218 0.88 MAPK1 (0.34) GRM5MAPK1KITMETKDM1A
SCHEMBL27247160 0.88 EPHX2 (0.37) EPHX2CYP2C9CYP2J2MAPK1ENPP2
SCHEMBL27247257 0.87 ALK (0.34) EPHX2GRM5MAPK1MET
SCHEMBL27247213 0.87 SCD (0.33) MAPK1
SCHEMBL30946212 0.86 MET (0.35) GRM5MAPK1KITMETKDM1A
SCHEMBL30946072 0.86 MAPK1 (0.36) CYP2C9GRM5MAPK1MET
SCHEMBL30920146 0.86 GRM5 (0.37) EPHX2CYP2C9CYP2J2GRM5MAPK1
SCHEMBL27247071 0.86 GRM5 (0.37) EPHX2CYP2C9CYP2J2GRM5MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed
WO-2024081748-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-04-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 EPHX2 3370/4885CYP2C9 302/4885CYP2J2 4220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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