SCHEMBL30920709

SCHEMBL30920709

COc1ccc2cc(CNC(=O)C3(C)CC3)[nH]c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MTNR1A P48039 3/20 0.57
▸ MTNR1B P49286 2/20 0.57
▸ KMT2A Q03164 3/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ KDM4E B2RXH2 7/20 0.44
▸ HSD17B10 Q99714 7/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ NPC1 O15118 4/20 0.44
▸ RAB9A P51151 4/20 0.44
▸ MAPT P10636 2/20 0.44
▸ TP53 P04637 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ PDGFRB P09619 1/20 0.43
▸ PDGFRA P16234 1/20 0.43
▸ FLT3 P36888 1/20 0.43
▸ TSHR P16473 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HRH4 Q9H3N8 1/20 0.42
▸ HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30920247 0.85 MTNR1A (0.41) MTNR1AMTNR1BKMT2AMEN1KDM4E
SCHEMBL27248068 0.85 MTNR1A (0.41) MTNR1AMTNR1BKMT2AMEN1KDM4E
SCHEMBL27247390 0.84 METTL3 (0.39) MTNR1AMTNR1BNPC1RAB9AFLT3
SCHEMBL27247424 0.84 MAOB (0.49) MTNR1AMTNR1BKMT2AMEN1KDM4E
SCHEMBL27247738 0.83 METTL3 (0.38) MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2
SCHEMBL27246874 0.83 HRH4 (0.40) MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2
SCHEMBL30920223 0.83 HRH4 (0.40) MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2
SCHEMBL27383634 0.83 DAO (0.46) RAB9ASMN1; SMN2
SCHEMBL27247898 0.83 RAB9A (0.40) MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1
SCHEMBL27247600 0.83 MTNR1A (0.40) MTNR1AMTNR1BKMT2AMEN1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
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