SCHEMBL27246874

SCHEMBL27246874

CC1(C(=O)NCc2cc3ccc(N)cc3[nH]2)CC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HRH4 Q9H3N8 1/20 0.40
▸ METTL3 Q86U44 11/20 0.38
▸ METTL14 Q9HCE5 11/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ RAB9A P51151 2/20 0.37
▸ MTNR1A P48039 2/20 0.37
▸ MTNR1B P49286 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL27247438 0.93 METTL3 (0.37) HRH4METTL3METTL14SMN1; SMN2RAB9A
SCHEMBL27247390 0.86 METTL3 (0.39) HRH4METTL3METTL14SMN1; SMN2RAB9A
SCHEMBL27383634 0.85 DAO (0.46) METTL3METTL14SMN1; SMN2RAB9A
SCHEMBL27247738 0.85 METTL3 (0.38) METTL3METTL14SMN1; SMN2RAB9AMTNR1A
SCHEMBL30920223 0.85 HRH4 (0.40) HRH4METTL3METTL14SMN1; SMN2RAB9A
SCHEMBL30920709 0.83 MTNR1A (0.57) HRH4SMN1; SMN2RAB9AMTNR1AMTNR1B
SCHEMBL27383636 0.83 EIF4A3 (0.47) METTL3METTL14SMN1; SMN2RAB9AMTNR1A
SCHEMBL27247099 0.82 HRH4 (0.45) HRH4METTL3METTL14SMN1; SMN2
SCHEMBL27382334 0.82 RAB9A (0.40) METTL3METTL14SMN1; SMN2RAB9AMTNR1A
SCHEMBL30920247 0.78 MTNR1A (0.41) METTL3METTL14SMN1; SMN2RAB9AMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed
WO-2024081748-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-04-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 HRH4 2480/4885METTL3 2034/4885METTL14 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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