Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26144979 | 1.00 | LMNA (0.39) | LMNAMBTD1L3MBTL3ATMMMP2 | |
| SCHEMBL28762826 | 0.80 | KMT2A (0.49) | LMNAKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL17364184 | 0.77 | ATM (0.45) | MBTD1L3MBTL3ATMMMP2KMT2A | |
| SCHEMBL8557186 | 0.75 | CHRM1 (0.49) | MBTD1L3MBTL3ATMMMP2HTR7 | |
| SCHEMBL263686 | 0.74 | ATM (0.46) | ATMMMP2HSD17B2L3MBTL1EDNRB | |
| SCHEMBL28605173 | 0.74 | ATM (0.43) | MBTD1L3MBTL3ATMMMP2KMT2A | |
| SCHEMBL1369921 | 0.74 | CA2 (0.47) | ATMMMP2HSD17B2 | |
| SCHEMBL29782813 | 0.74 | ATM (0.43) | MBTD1L3MBTL3ATMMMP2KMT2A | |
| SCHEMBL17699828 | 0.74 | ATM (0.43) | MBTD1L3MBTL3ATMMMP2KMT2A | |
| SCHEMBL4251866 | 0.73 | PLCG1 (0.56) | MBTD1L3MBTL3ATMMMP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241504-A | Spiroindoline inhibitors of KIF18A | 沃拉斯查疗法公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118103352-A | Spiroindoline inhibitors of KIF18A | 沃拉斯查疗法公司 | 2024-05-28 | — | — | CN | disclosed |