Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214297 | 1.00 | MET (0.49) | METGRM5SLC40A1HPGDALDH1A1 | |
| SCHEMBL30925530 | 0.91 | MET (0.52) | METSLC40A1HPGDALDH1A1MEN1 | |
| SCHEMBL27214195 | 0.85 | SLC40A1 (0.47) | SLC40A1ALDH1A1MEN1S1PR4LMNA | |
| SCHEMBL30925573 | 0.85 | SLC40A1 (0.47) | SLC40A1ALDH1A1MEN1S1PR4LMNA | |
| SCHEMBL27214253 | 0.74 | SLC40A1 (0.48) | SLC40A1ALDH1A1MEN1S1PR4LMNA | |
| SCHEMBL30925406 | 0.74 | SLC40A1 (0.48) | SLC40A1ALDH1A1MEN1S1PR4LMNA | |
| SCHEMBL30925566 | 0.69 | SCN9A (0.52) | SLC40A1HPGDALDH1A1MEN1LMNA | |
| SCHEMBL27214257 | 0.69 | SCN9A (0.52) | SLC40A1HPGDALDH1A1MEN1LMNA | |
| SCHEMBL13485931 | 0.67 | SLC40A1 (0.60) | SLC40A1ALDH1A1MEN1S1PR4LMNA | |
| SCHEMBL29800777 | 0.66 | SLC40A1 (0.42) | SLC40A1HPGDALDH1A1MEN1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ZOETIS LLC | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ARSA, MRPS2, SULT2A1 | MET 3930/4885GRM5 2565/4885SLC40A1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.