Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 4/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648852 | 0.82 | MEN1 (0.50) | MMP9GSK3AGSK3BALDH1A1MEN1 | |
| SCHEMBL3086045 | 0.75 | MMP2 (0.63) | EHMT2MMP2MMP9GSK3AGSK3B | |
| SCHEMBL3088377 | 0.75 | MMP2 (0.49) | EHMT2MMP2MMP9GSK3AGSK3B | |
| SCHEMBL28859277 | 0.74 | EHMT2 (0.47) | EHMT2MMP2MMP9GSK3AGSK3B | |
| SCHEMBL28859279 | 0.74 | EHMT2 (0.47) | EHMT2MMP2MMP9GSK3AGSK3B | |
| SCHEMBL8293421 | 0.73 | EHMT2 (0.46) | EHMT2GSK3AGSK3BALDH1A1TDP1 | |
| SCHEMBL22443716 | 0.73 | TP53 (0.46) | EHMT2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL22443715 | 0.73 | TP53 (0.46) | EHMT2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL29135687 | 0.72 | EHMT2 (0.45) | EHMT2ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29135683 | 0.72 | EHMT2 (0.45) | EHMT2ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799929-B2 | Biotin intermediate and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-1462444-B1 | INTERMEDIATE FOR BIOTIN AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-09-16 | — | — | EP | disclosed |
| EP-2098528-A2 | Biotin intermediate and process for preparing the same | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20080119655-A1 | Biotin intermediate and process for preparing the same | SEKI MASAHIKO | 2008-05-22 | — | — | US | disclosed |
| US-7335778-B2 | Intermediate for biotin and process for producing the same | TANABE SEIYAKU CO., LTD. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20050038260-A1 | Intermediate for biotin and process for producing the same | API CORPORATION (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1462444-A1 | INTERMEDIATE FOR BIOTIN AND PROCESS FOR PRODUCING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119655-A1 | Biotin intermediate and process for preparing the same | BTD, BOLA2; BOLA2B, BCAT1 | EHMT2 308/4885MMP2 3977/4885MMP9 4356/4885 |
| US-20050038260-A1 | Intermediate for biotin and process for producing the same | BTD, BCAT1, HLCS | EHMT2 388/4885MMP2 3330/4885MMP9 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.